UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 12 von 78
Datensatz exportieren als...
BibTeX
Aspirin Use and Reduced Risk of Pancreatic Cancer
Cancer epidemiology, biomarkers & prevention, 2017-01, Vol.26 (1), p.68-74
Risch, Harvey A
Lu, Lingeng
Streicher, Samantha A
Wang, Jing
Zhang, Wei
Ni, Quanxing
Kidd, Mark S
Yu, Herbert
Gao, Yu-Tang
2017
Volltextzugriff (PDF)
Details
Autor(en) / Beteiligte
Risch, Harvey A
Lu, Lingeng
Streicher, Samantha A
Wang, Jing
Zhang, Wei
Ni, Quanxing
Kidd, Mark S
Yu, Herbert
Gao, Yu-Tang
Titel
Aspirin Use and Reduced Risk of Pancreatic Cancer
Ist Teil von
Cancer epidemiology, biomarkers & prevention, 2017-01, Vol.26 (1), p.68-74
Ort / Verlag
United States: American Association for Cancer Research, Inc
Erscheinungsjahr
2017
Quelle
EZB-FREE-00999 freely available EZB journals
Beschreibungen/Notizen
Few options besides the avoidance of smoking and obesity are available to prevent pancreatic cancer. The association between aspirin use and risk of pancreatic cancer has been inconsistent across studies. We performed a population-based study of 761 case and 794 control subjects frequency matched on sex and age during 2006 to 2011 in Shanghai, China. Participants were asked about episodes of regular use of aspirin, tablets per day or week, and ages that the use started and stopped. Data were analyzed by unconditional logistic regression, with adjustments for age, sex, education, body mass index, years of cigarette smoking, cigarettes smoked per day, Helicobacter pylori CagA seropositivity, ABO blood group, and history of diabetes mellitus. Meta-regression was carried out to summarize the literature. Ever-regular use of aspirin was associated with lowered risk of pancreatic cancer: OR = 0.54; 95% confidence interval (CI), 0.40-0.73; P = 10 Risk decreased 8% per each cumulative year of use: OR = 0.92; 95% CI, 0.87-0.97; P = 0.0034. Across this and 18 published studies of this association, the OR for ever-regular use decreased with increasingly more recent mid-study year, for any aspirin type (P = 10 ), and for low-dose aspirin (P = 0.0014). Regular use of aspirin thus appears to reduce risk of pancreatic cancer by almost half. People who take aspirin for prevention of other diseases likely also reduce their risk of pancreatic cancer. Aside from benefits for both cardiovascular disease and certain cancers, long-term aspirin use entails some risks of bleeding complications, which necessitates risk-benefit analysis for individual decisions about use. Cancer Epidemiol Biomarkers Prev; 26(1); 68-74. ©2016 AACR.
Sprache
Englisch
Identifikatoren
ISSN: 1055-9965
eISSN: 1538-7755
DOI: 10.1158/1055-9965.EPI-16-0508
Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_5225096
Format
–
Schlagworte
ABO system
,
Age Factors
,
Aged
,
Aspirin
,
Aspirin - therapeutic use
,
Blood groups
,
Body mass
,
Body mass index
,
Cardiovascular diseases
,
Case-Control Studies
,
China - epidemiology
,
Cigarette smoking
,
Complications
,
Data processing
,
Diabetes mellitus
,
Dose-Response Relationship, Drug
,
Drug Administration Schedule
,
Female
,
Health risk assessment
,
Health risks
,
Helicobacter pylori
,
Humans
,
Incidence
,
Logistic Models
,
Male
,
Middle Aged
,
Odds Ratio
,
Pancreatic cancer
,
Pancreatic Neoplasms - epidemiology
,
Pancreatic Neoplasms - prevention & control
,
Population studies
,
Prognosis
,
Reference Values
,
Retrospective Studies
,
Sex Factors
,
Smoking
,
Tablets
,
Urban Population
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX