Details

Autor(en) / Beteiligte

• Freire Dos Santos, Leandro
• Rubel, Rosália
• Bonatto, Sandro José Ribeiro
• Zanatta, Ana Lucia
• Aikawa, Júlia
• Yamaguchi, Adriana Aya
• Torres, Maria Fernanda
• Soccol, Vanete Thomaz
• Habu, Sascha
• Prado, Karin Braun
• Soccol, Carlos Ricardo

Titel

Cordyceps sinensis biomass produced by submerged fermentation in high-fat diet feed rats normalizes the blood lipid and the low testosterone induced by diet

Ist Teil von

• EXCLI journal, 2012-01, Vol.11, p.767-775

Ort / Verlag

Germany: Leibniz Research Centre for Working Environment and Human Factors

Erscheinungsjahr

2012

Quelle

EZB Free E-Journals

Beschreibungen/Notizen

• This study investigated the effect of biomass supplementation obtained from submerged fermentation on blood lipid and low testosterone induced by high-fat diet (HFD). The experiments were carried out using a long-term intake of HFD and HFD plus Simvastatin or (4 months). Our results show that plasma cholesterol, triglycerides and LDL were decreased by biomass supplementation (CSBS). A long-term intake of HFD caused a significant liver damage which has been reverted by CSBS. CSBS normalized decreasing testosterone levels observed in high-fat diet feed rats. All these findings lead us to suggest that was able to decrease blood lipid concentration, increase hepatoprotective activity and normalize testosterone levels.