Details

Autor(en) / Beteiligte

• Cohen, Myron S
• Chen, Ying Q
• McCauley, Marybeth
• Gamble, Theresa
• Hosseinipour, Mina C
• Kumarasamy, Nagalingeswaran
• Hakim, James G
• Kumwenda, Johnstone
• Grinsztejn, Beatriz
• Pilotto, Jose H.S
• Godbole, Sheela V
• Chariyalertsak, Suwat
• Santos, Breno R
• Mayer, Kenneth H
• Hoffman, Irving F
• Eshleman, Susan H
• Piwowar-Manning, Estelle
• Cottle, Leslie
• Zhang, Xinyi C
• Makhema, Joseph
• Mills, Lisa A
• Panchia, Ravindre
• Faesen, Sharlaa
• Eron, Joseph
• Gallant, Joel
• Havlir, Diane
• Swindells, Susan
• Elharrar, Vanessa
• Burns, David
• Taha, Taha E
• Nielsen-Saines, Karin
• Celentano, David D
• Essex, Max
• Hudelson, Sarah E
• Redd, Andrew D
• Fleming, Thomas R

Titel

Antiretroviral Therapy for the Prevention of HIV-1 Transmission

Ist Teil von

• The New England journal of medicine, 2016-09, Vol.375 (9), p.830-839

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2016

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• In this report involving 1763 HIV-1 serodiscordant couples, the suppression of HIV-1 in the infected partner significantly decreased the transmission of genetically linked HIV-1 to the uninfected partner. Advances in the treatment and care of patients with human immunodeficiency virus type 1 (HIV-1) infection have led to dramatic reductions in the morbidity and mortality associated with this disease. 1 However, despite intensive public health initiatives aimed at HIV-1 prevention, more than 2 million new HIV-1 infections were reported in 2014 worldwide. 2 The global HIV-1 epidemic is primarily driven by sexual transmission. 2 Potent, durable HIV-1 prevention strategies are required to reduce the risk of viral transmission from infected persons to their sexual partners. Observational studies involving serodiscordant couples have suggested that antiretroviral therapy (ART) in persons with HIV-1 infection reduces . . .