Details

Autor(en) / Beteiligte

• Stevanato, Gabriele
• Hill-Cousins, Joseph T.
• Håkansson, Pär
• Roy, Soumya Singha
• Brown, Lynda J.
• Brown, Richard C. D.
• Pileio, Giuseppe
• Levitt, Malcolm H.

Titel

A Nuclear Singlet Lifetime of More than One Hour in Room-Temperature Solution

Ist Teil von

• Angewandte Chemie, 2015-03, Vol.127 (12), p.3811-3814

Ort / Verlag

Weinheim: WILEY-VCH Verlag

Erscheinungsjahr

2015

Link zum Volltext

Quelle

Alma/SFX Local Collection

Beschreibungen/Notizen

• Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are supremely important techniques with numerous applications in almost all branches of science. However, until recently, NMR methodology was limited by the time constant T1 for the decay of nuclear spin magnetization through contact with the thermal molecular environment. Long‐lived states, which are correlated quantum states of multiple nuclei, have decay time constants that may exceed T1 by large factors. Here we demonstrate a nuclear long‐lived state comprising two 13C nuclei with a lifetime exceeding one hour in room‐temperature solution, which is around 50 times longer than T1. This behavior is well‐predicted by a combination of quantum theory, molecular dynamics, and quantum chemistry. Such ultra‐long‐lived states are expected to be useful for the transport and application of nuclear hyperpolarization, which leads to NMR and MRI signals enhanced by up to five orders of magnitude. Lang lebe der Spin: Ein molekulares System basierend auf einem 13C2‐markierten Naphthalin‐Kern wurde hergestellt, das in Lösung eine langlebige Singulett‐Kernspinordnung unterstützt. Ein Singulett‐Kernspin mit einer Lebensdauer von über einer Stunde konnte in Lösung bei Raumtemperatur beobachtet werden.