Details

Autor(en) / Beteiligte

• Passalacqua, Karla D
• Charbonneau, Marie-Eve
• O'Riordan, Mary X D
• Kudva, Indira T.
• Cornick, Nancy A.

Titel

Bacterial Metabolism Shapes the Host-Pathogen Interface

Ist Teil von

• Microbiology spectrum, 2016-06, Vol.4 (3)

Ort / Verlag

United States: ASM Press

Erscheinungsjahr

2016

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• Bacterial pathogens have evolved to exploit humans as a rich source of nutrients to support survival and replication. The pathways of bacterial metabolism that permit successful colonization are surprisingly varied and highlight remarkable metabolic flexibility. The constraints and immune pressures of distinct niches within the human body set the stage for understanding the mechanisms by which bacteria acquire critical nutrients. In this article we discuss how different bacterial pathogens carry out carbon and energy metabolism in the host and how they obtain or use key nutrients for replication and immune evasion.