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Bacterial Metabolism Shapes the Host-Pathogen Interface
Ist Teil von
Microbiology spectrum, 2016-06, Vol.4 (3)
Ort / Verlag
United States: ASM Press
Erscheinungsjahr
2016
Quelle
EZB-FREE-00999 freely available EZB journals
Beschreibungen/Notizen
Bacterial pathogens have evolved to exploit humans as a rich source of nutrients to support survival and replication. The pathways of bacterial metabolism that permit successful colonization are surprisingly varied and highlight remarkable metabolic flexibility. The constraints and immune pressures of distinct niches within the human body set the stage for understanding the mechanisms by which bacteria acquire critical nutrients. In this article we discuss how different bacterial pathogens carry out carbon and energy metabolism in the host and how they obtain or use key nutrients for replication and immune evasion.