Details

Autor(en) / Beteiligte

• Goldstein, Daniel
• Moskowitz, Alan J
• Gelijns, Annetine C
• Ailawadi, Gorav
• Parides, Michael K
• Perrault, Louis P
• Hung, Judy W
• Voisine, Pierre
• Dagenais, Francois
• Gillinov, A. Marc
• Thourani, Vinod
• Argenziano, Michael
• Gammie, James S
• Mack, Michael
• Demers, Philippe
• Atluri, Pavan
• Rose, Eric A
• O’Sullivan, Karen
• Williams, Deborah L
• Bagiella, Emilia
• Michler, Robert E
• Weisel, Richard D
• Miller, Marissa A
• Geller, Nancy L
• Taddei-Peters, Wendy C
• Smith, Peter K
• Moquete, Ellen
• Overbey, Jessica R
• Kron, Irving L
• O’Gara, Patrick T
• Acker, Michael A

Titel

Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation

Ist Teil von

• The New England journal of medicine, 2016-01, Vol.374 (4), p.344-353

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2016

Quelle

MEDLINE

Beschreibungen/Notizen

• Among patients with severe ischemic mitral regurgitation who were assigned to mitral-valve repair or replacement, there were no significant between-group differences in left ventricular remodeling or mortality at 2 years. Mitral regurgitation recurred more frequently in the repair group. Ischemic mitral regurgitation is a serious consequence of coronary artery disease that carries a substantial risk of death from cardiovascular causes in proportion to its severity. 1 , 2 Ischemic mitral regurgitation is anatomically characterized by remodeling or distortion of left ventricular geometry that ultimately results in papillary-muscle displacement, leaflet tethering, and impaired coaptation. For the subgroup of patients with severe ischemic mitral regurgitation, the prognosis is grave, with rates of death ranging from 15 to 40% at 1 year. 2 – 4 For patients with severe ischemic mitral regurgitation, the benefit of surgical revascularization is undisputed, provided that the patient has suitable coronary . . .