Details

Autor(en) / Beteiligte

• Cheung, Celeste H. M.
• Rijsdijk, Fruhling
• McLoughlin, Gráinne
• Brandeis, Daniel
• Banaschewski, Tobias
• Asherson, Philip
• Kuntsi, Jonna

Titel

Cognitive and neurophysiological markers of ADHD persistence and remission

Ist Teil von

• British journal of psychiatry, 2016-06, Vol.208 (6), p.548-555

Ort / Verlag

Cambridge, UK: Cambridge University Press

Erscheinungsjahr

2016

Link zum Volltext

Quelle

Applied Social Sciences Index & Abstracts (ASSIA)

Beschreibungen/Notizen

• Attention-deficit hyperactivity disorder (ADHD) persists in around two-thirds of individuals in adolescence and early adulthood. To examine the cognitive and neurophysiological processes underlying the persistence or remission of ADHD. Follow-up data were obtained from 110 young people with childhood ADHD and 169 controls on cognitive, electroencephalogram frequency, event-related potential (ERP) and actigraph movement measures after 6 years. ADHD persisters differed from remitters on preparation-vigilance measures (contingent negative variation, delta activity, reaction time variability and omission errors), IQ and actigraph count, but not on executive control measures of inhibition or working memory (nogo-P3 amplitudes, commission errors and digit span backwards). Preparation-vigilance measures were markers of remission, improving concurrently with ADHD symptoms, whereas executive control measures were not sensitive to ADHD persistence/remission. For IQ, the present and previous results combined suggest a role in moderating ADHD outcome. These findings fit with previously identified aetiological separation of the cognitive impairments in ADHD. The strongest candidates for the development of non-pharmacological interventions involving cognitive training and neurofeedback are the preparation-vigilance processes that were markers of ADHD remission.