Journal of autism and developmental disorders, 2016-06, Vol.46 (6), p.2064-2071
2016
Details
- Autor(en) / Beteiligte
- Titel
- Dissociation of Cross-Sectional Trajectories for Verbal and Visuo-Spatial Working Memory Development in Rubinstein-Taybi Syndrome
- Ist Teil von
- Journal of autism and developmental disorders, 2016-06, Vol.46 (6), p.2064-2071
- Ort / Verlag
- New York: Springer US
- Erscheinungsjahr
- 2016
- Link zum Volltext
- Quelle
- Applied Social Sciences Index & Abstracts (ASSIA)
- Beschreibungen/Notizen
- Working memory (WM) impairments might amplify behavioural difference in genetic syndromes. Murine models of Rubinstein–Taybi syndrome (RTS) evidence memory impairments but there is limited research on memory in RTS. Individuals with RTS and typically developing children completed WM tasks, with participants with RTS completing an IQ assessment and parents/carers completing the Vineland Adaptive Behavior Scales. A cross-sectional trajectory analysis was conducted. There were significant WM span deficits in RTS relative to mental age. Verbal WM span was positively associated with mental age; however, this was not observed for visuo-spatial span. There is a dissociation between WM domains in RTS. Individuals may have difficulties with tasks relying on WM span, above difficulties predicted by overall ability.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0162-3257eISSN: 1573-3432DOI: 10.1007/s10803-016-2736-2Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4860195
- Format
- –
- Schlagworte
- Adaptive behavior, Adolescent, Adult, Animal models, Autism, Behavior, Behavioral Science and Psychology, Caregivers, Child, Child and School Psychology, Child, Preschool, Children, Cognition & reasoning, Cognitive Ability, Cognitive Processes, Complications and side effects, Cross-Sectional Studies, Developmental Disabilities, Developmental Tasks, Dissociation, England (West Midlands), Female, Foreign Countries, Genetic Disorders, Genetic engineering, Humans, Information processing, Intellectual disabilities, Language, Male, Memory, Memory Disorders - diagnosis, Memory Disorders - epidemiology, Memory Disorders - physiopathology, Memory, Short-Term - physiology, Mental Age, Mullen Scales of Early Learning, Neurosciences, Original Paper, Pediatrics, Phonology, Physiological aspects, Psychological aspects, Psychology, Public Health, Reading Comprehension, Regression (Statistics), Rubinstein-Taybi syndrome, Rubinstein-Taybi Syndrome - diagnosis, Rubinstein-Taybi Syndrome - epidemiology, Rubinstein-Taybi Syndrome - physiopathology, Short term, Short Term Memory, Spatial Ability, Spatial discrimination, Spatial memory, Statistical Analysis, Verbal Ability, Verbal Development, Verbal Learning - physiology, Verbal memory, Vineland Adaptive Behavior Scales, Vocabulary Development, Wechsler Intelligence Scales Short Forms, Wilcoxon Matched Pairs Signed Ranks Test, Young Adult