Journal of virology, 2016-05, Vol.90 (10), p.4860-4863
2016
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Details
- Autor(en) / Beteiligte
- Titel
- Hepatitis C Virus Exploitation of Processing Bodies
- Ist Teil von
- Journal of virology, 2016-05, Vol.90 (10), p.4860-4863
- Ort / Verlag
- United States: American Society for Microbiology
- Erscheinungsjahr
- 2016
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- During infection, positive-strand RNA viruses subvert cellular machinery involved in RNA metabolism to translate viral proteins and replicate viral genomes to avoid or disable the host defense mechanisms. Cytoplasmic RNA granules modulate the stabilities of cellular and viral RNAs. Understanding how hepatitis C virus and other flaviviruses interact with the host machinery required for protein synthesis, localization, and degradation of mRNAs is important for elucidating how these processes occur in both virus-infected and uninfected cells.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0022-538XeISSN: 1098-5514DOI: 10.1128/jvi.03056-15Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4859705
- Format
- –
- Schlagworte
- Cytoplasmic Granules - genetics, Cytoplasmic Granules - immunology, Cytoplasmic Granules - metabolism, Cytoplasmic Granules - ultrastructure, Gems, Genome, Viral, Hepacivirus - genetics, Hepacivirus - immunology, Hepacivirus - physiology, Hepatitis C virus, Host-Pathogen Interactions, Humans, MicroRNAs - metabolism, RNA, Messenger - genetics, RNA, Messenger - metabolism, RNA, Small Interfering - immunology, RNA, Viral - genetics, RNA, Viral - metabolism