Details

Autor(en) / Beteiligte

• Cooper, Christopher J
• Murphy, Timothy P
• Cutlip, Donald E
• Jamerson, Kenneth
• Henrich, William
• Reid, Diane M
• Cohen, David J
• Matsumoto, Alan H
• Steffes, Michael
• Jaff, Michael R
• Prince, Martin R
• Lewis, Eldrin F
• Tuttle, Katherine R
• Shapiro, Joseph I
• Rundback, John H
• Massaro, Joseph M
• D'Agostino, Ralph B
• Dworkin, Lance D

Titel

Stenting and Medical Therapy for Atherosclerotic Renal-Artery Stenosis

Ist Teil von

• The New England journal of medicine, 2014-01, Vol.370 (1), p.13-22

Ort / Verlag

Waltham, MA: Massachusetts Medical Society

Erscheinungsjahr

2014

Quelle

MEDLINE

Beschreibungen/Notizen

• In this trial, 947 patients with renal-artery stenosis were assigned to renal-artery stenting or medical therapy. At a median of 43 months, there was no significant between-group difference in the rate of a composite end point of adverse cardiovascular and renal events. Renal-artery stenosis, which is present in 1 to 5% of people with hypertension, 1 , 2 often occurs in combination with peripheral arterial or coronary artery disease. 3 , 4 Results of community-based screening suggest that the prevalence among persons older than 65 years of age may be as high as 7%. 5 Renal-artery stenosis may result in hypertension, ischemic nephropathy, and multiple long-term complications. 6 Uncontrolled studies performed in the 1990s suggested that renal-artery angioplasty or stenting resulted in significant reductions in systolic blood pressure 7 , 8 and in the stabilization of chronic kidney disease. 9 , 10 Subsequently, there were rapid increases in the rate of renal-artery . . .