The FEBS journal, 2016-03, Vol.283 (6), p.986-992
2016
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Details
- Autor(en) / Beteiligte
- Titel
- Structures of the double‐ring AAA ATPase Pex1–Pex6 involved in peroxisome biogenesis
- Ist Teil von
- The FEBS journal, 2016-03, Vol.283 (6), p.986-992
- Ort / Verlag
- England: Blackwell Publishing Ltd
- Erscheinungsjahr
- 2016
- Quelle
- Wiley-Blackwell Journals
- Beschreibungen/Notizen
- The Pex1 and Pex6 proteins are members of the AAA family of ATPases and are involved in peroxisome biogenesis. Recently, cryo‐electron microscopy structures of the Pex1–Pex6 complex in different nucleotide states have been determined. This Structural Snapshot describes the structural features of the complex and their implications for its function, as well as questions that still await answers. The Pex1/Pex6 complex is a member of the AAA family of ATPases that is involved in peroxisome biogenesis. Recently, cryo‐electron microscopy structures have been determined of the Pex1/Pex6 complex in different nucleotide states. This Structural Snapshot describes the structural features of the complex, their implications for its function, as well as questions that still await answers.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1742-464XeISSN: 1742-4658DOI: 10.1111/febs.13569Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4803591
- Format
- –
- Schlagworte
- AAA ATPases, Adenosine Triphosphatases - chemistry, Adenosine Triphosphatases - metabolism, ATPases Associated with Diverse Cellular Activities, Biosynthesis, Cryoelectron Microscopy, cryo‐electron microscopy, Enzymes, Humans, Membrane Proteins - chemistry, Membrane Proteins - metabolism, Models, Molecular, Molecular biology, Multienzyme Complexes - chemistry, Multienzyme Complexes - metabolism, peroxisome biogenesis, Peroxisomes - enzymology, Pex1–Pex6 complex, Protein Conformation, Protein Interaction Domains and Motifs, Protein Subunits, single‐particle analysis, Static Electricity