Details

Autor(en) / Beteiligte

• Wright, Jr, Jackson T
• Williamson, Jeff D
• Whelton, Paul K
• Snyder, Joni K
• Sink, Kaycee M
• Rocco, Michael V
• Reboussin, David M
• Rahman, Mahboob
• Oparil, Suzanne
• Lewis, Cora E
• Kimmel, Paul L
• Johnson, Karen C
• Goff, Jr, David C
• Fine, Lawrence J
• Cutler, Jeffrey A
• Cushman, William C
• Cheung, Alfred K
• Ambrosius, Walter T

Titel

A Randomized Trial of Intensive versus Standard Blood-Pressure Control

Ist Teil von

• The New England journal of medicine, 2015-11, Vol.373 (22), p.2103-2116

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• Patients at increased cardiovascular risk but without diabetes were assigned to intensive treatment of systolic BP (target, <120 mm Hg) or standard treatment (target, <140 mm Hg). After a median of 3.26 years, the rate of cardiovascular events was significantly lower with intensive treatment. Hypertension is highly prevalent in the adult population in the United States, especially among persons older than 60 years of age, and affects approximately 1 billion adults worldwide. 1 , 2 Among persons 50 years of age or older, isolated systolic hypertension is the most common form of hypertension, 3 , 4 and systolic blood pressure becomes more important than diastolic blood pressure as an independent risk predictor for coronary events, stroke, heart failure, and end-stage renal disease (ESRD). 5 – 13 The Global Burden of Disease Study identified elevated blood pressure as the leading risk factor, among 67 studied, for death and disability-adjusted life-years lost . . .