Details

Autor(en) / Beteiligte

• Drost, J.T.
• Grutters, J.P.C.
• van der Wilt, G.-J.
• van der Schouw, Y.T.
• Maas, A.H.E.M.

Titel

Yearly hypertension screening in women with a history of pre-eclampsia: a cost-effectiveness analysis

Ist Teil von

• Netherlands heart journal, 2015-12, Vol.23 (12), p.585-591

Ort / Verlag

Houten: Bohn Stafleu van Loghum

Erscheinungsjahr

2015

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Background Women with a history of preeclampsia are at increased risk for future hypertension and cardiovascular disease (CVD); until now it is not clear whether preventive measures are needed. Methods A decision-analytic Markov model was constructed to evaluate healthcare costs and effects of screening and treatment (100 % compliance) for hypertension post preeclampsia based on the available literature. Cardiovascular events and CVD mortality were defined as health states. Outcomes were measured in absolute costs, events, life-years and quality-adjusted life-years (QALYs). Sensitivity and threshold analyses were performed to address uncertainty. Results Over a 20-year time horizon, events occurred in 7.2 % of the population after screening, and in 8.5 % of the population without screening. QALYs increased from 16.37 (no screening strategy) to 16.40 (screening strategy), an increment of 0.03 (95 % CI 0.01;0.05) QALYs. Total expected costs were € 8016 in the screening strategy, and € 9087 in the none screening strategy (expected saving of € 1071 (95 % CI − 3146;-87) per person). Conclusion Annual hypertension screening and treatment in women with a history of preeclampsia may save costs, for at least a similar quality of life and survival due to prevented CVD compared with standard care.