Details

Autor(en) / Beteiligte

• Clayton, Andrew H.A.
• Chattopadhyay, Amitabha

Titel

Get Your kICS by Measuring Membrane Protein Dynamics

Ist Teil von

• Biophysical journal, 2015-07, Vol.109 (1), p.1-2

Ort / Verlag

United States: Elsevier Inc

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• Akin to the puck on an ice hockey rink, the lateral dynamics of a representative membrane protein exhibits rich behavior (1). Depending on the interaction with the hockey players and other obstacles (membrane constituents), the puck (protein) can dart around the ice (membrane surface) or be stalled momentarily (transient confinement zone). If we watched the motion of a single puck, we would need to watch many hockey games before we might eventually work out the rules of the game. But what if we could watch many games in parallel? This is where the suite of image correlation spectroscopy (ICS) techniques and its newest member, k-space image correlation spectroscopy (kICS) comes in Abu-Arish et al.