Advanced healthcare materials, 2015-08, Vol.4 (12), p.1813-1818
2015
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Details
- Autor(en) / Beteiligte
- Titel
- Selenite-Releasing Bone Mineral Nanoparticles Retard Bone Tumor Growth and Improve Healthy Tissue Functions In Vivo
- Ist Teil von
- Advanced healthcare materials, 2015-08, Vol.4 (12), p.1813-1818
- Ort / Verlag
- Germany: Blackwell Publishing Ltd
- Erscheinungsjahr
- 2015
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Selenite‐doped bone mineral nanoparticles can retard the growth of osteosarcoma in a nude mice model, through sustained release of selenite ions. The selenite ions released from the nanoparticles through a degradation‐mediated fashion inhibit tumor metastasis. Blood routine analysis indicates that selenite ions can also improve the functions of liver, kidney, and heart.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 2192-2640eISSN: 2192-2659DOI: 10.1002/adhm.201500307Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4551614
- Format
- –
- Schlagworte
- Animals, Biocompatibility, Biocompatible Materials - chemistry, Biocompatible Materials - pharmacology, Biomedical materials, Bone Density - drug effects, bone minerals, Bone Neoplasms - drug therapy, Bones, Durapatite - chemistry, Durapatite - pharmacology, hydroxyapatite, Mathematical models, Mice, Mice, Nude, Minerals, Nanoparticles, Nanoparticles - chemistry, osteosarcoma, Selenious Acid - chemistry, Selenious Acid - pharmacology, selenite, Selenites, Tumors