Details

Autor(en) / Beteiligte

• Nolen, Leisha Diane
• Osadebe, Lynda
• Katomba, Jacques
• Likofata, Jacques
• Mukadi, Daniel
• Monroe, Benjamin
• Doty, Jeffrey
• Kalemba, Lem's
• Malekani, Jean
• Kabamba, Joelle
• Bomponda, Pierre Lokwa
• Lokota, Jules Inonga
• Balilo, Marcel Pie
• Likafi, Toutou
• Lushima, Robert Shongo
• Tamfum, Jean-Jacques Muyembe
• Okitolonda, Emile Wemakoy
• McCollum, Andrea M
• Reynolds, Mary G

Titel

Introduction of Monkeypox into a Community and Household: Risk Factors and Zoonotic Reservoirs in the Democratic Republic of the Congo

Ist Teil von

• The American journal of tropical medicine and hygiene, 2015-08, Vol.93 (2), p.410-415

Ort / Verlag

United States: The American Society of Tropical Medicine and Hygiene

Erscheinungsjahr

2015

Link zum Volltext

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• An increased incidence of monkeypox (MPX) infections in the Democratic Republic of the Congo was noted by the regional surveillance system in October 2013. Little information exists regarding how MPX is introduced into the community and the factors associated with transmission within the household. Sixty-eight wild animals were collected and tested for Orthopoxvirus. Two of three rope squirrels (Funisciurus sp.) were positive for antibodies to Orthopoxviruses; however, no increased risk was associated with the consumption or preparation of rope squirrels. A retrospective cohort investigation and a case-control investigation were performed to identify risk factors affecting the introduction of monkeypox virus (MPXV) into the community and transmission within the home. School-age males were the individuals most frequently identified as the first person infected in the household and were the group most frequently affected overall. Risk factors of acquiring MPXV in a household included sleeping in the same room or bed, or using the same plate or cup as the primary case. There was no significant risk associated with eating or processing of wild animals. Activities associated with an increased risk of MPXV transmission all have potential for virus exposure to the mucosa.