Details

Autor(en) / Beteiligte

• Moler, Frank W
• Silverstein, Faye S
• Holubkov, Richard
• Slomine, Beth S
• Christensen, James R
• Nadkarni, Vinay M
• Meert, Kathleen L
• Clark, Amy E
• Browning, Brittan
• Pemberton, Victoria L
• Page, Kent
• Shankaran, Seetha
• Hutchison, Jamie S
• Newth, Christopher J.L
• Bennett, Kimberly S
• Berger, John T
• Topjian, Alexis
• Pineda, Jose A
• Koch, Joshua D
• Schleien, Charles L
• Dalton, Heidi J
• Ofori-Amanfo, George
• Goodman, Denise M
• Fink, Ericka L
• McQuillen, Patrick
• Zimmerman, Jerry J
• Thomas, Neal J
• van der Jagt, Elise W
• Porter, Melissa B
• Meyer, Michael T
• Harrison, Rick
• Pham, Nga
• Schwarz, Adam J
• Nowak, Jeffrey E
• Alten, Jeffrey
• Wheeler, Derek S
• Bhalala, Utpal S
• Lidsky, Karen
• Lloyd, Eric
• Mathur, Mudit
• Shah, Samir
• Wu, Theodore
• Theodorou, Andreas A
• Sanders, Ronald C
• Dean, J. Michael

Titel

Therapeutic Hypothermia after Out-of-Hospital Cardiac Arrest in Children

Ist Teil von

• The New England journal of medicine, 2015-05, Vol.372 (20), p.1898-1908

Ort / Verlag

United States: Massachusetts Medical Society

Erscheinungsjahr

2015

Quelle

MEDLINE

Beschreibungen/Notizen

• This study of targeted temperature interventions in 295 children who were comatose after cardiac arrest showed no significant difference between the hypothermia group (33.0°C) and the normothermia group (36.8°C) with respect to 1-year survival with a good functional outcome. Out-of-hospital cardiac arrest in children often results in death or in poor long-term functional outcome in survivors. 1 – 3 In 2002, two trials involving adults showed that therapeutic hypothermia improved neurologic outcomes in comatose survivors after out-of-hospital cardiac arrest with ventricular fibrillation or ventricular tachycardia. 4 , 5 International guidelines recommend therapeutic hypothermia for adults with out-of-hospital cardiac arrest who have similar characteristics. 6 , 7 Recently, another trial involving adults after out-of-hospital cardiac arrest showed that therapeutic hypothermia with the use of a target temperature of 33°C, as compared with actively maintained therapeutic normothermia (36°C), did not improve outcomes. 8 The fundamental difference between this . . .