Details

Autor(en) / Beteiligte

• Gutiérrez, Serafín
• Thébaud, Gaël
• Smith, Darci R
• Kenney, Joan L
• Weaver, Scott C
• Diamond, M. S.

Titel

Demographics of natural oral infection of mosquitos by Venezuelan equine encephalitis virus

Ist Teil von

• Journal of virology, 2015-04, Vol.89 (7), p.4020-4022

Ort / Verlag

United States: American Society for Microbiology

Erscheinungsjahr

2015

Link zum Volltext

Quelle

Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals

Beschreibungen/Notizen

• The within-host diversity of virus populations can be drastically limited during between-host transmission, with primary infection of hosts representing a major constraint to diversity maintenance. However, there is an extreme paucity of quantitative data on the demographic changes experienced by virus populations during primary infection. Here, the multiplicity of cellular infection (MOI) and population bottlenecks were quantified during primary mosquito infection by Venezuelan equine encephalitis virus, an arbovirus causing neurological disease in humans and equids.