Details

Autor(en) / Beteiligte

• Toro‐Ramos, Tatiana
• Goodpaster, Bret H.
• Janumala, Isaiah
• Lin, Susan
• Strain, Gladys W.
• Thornton, John C.
• Kang, Patrick
• Courcoulas, Anita P.
• Pomp, Alfons
• Gallagher, Dympna

Titel

Continued loss in visceral and intermuscular adipose tissue in weight‐stable women following bariatric surgery

Ist Teil von

• Obesity (Silver Spring, Md.), 2015-01, Vol.23 (1), p.62-69

Ort / Verlag

United States: Blackwell Publishing Ltd

Erscheinungsjahr

2015

Quelle

Wiley Blackwell Single Titles

Beschreibungen/Notizen

• Objective To assess changes in total (TAT), subcutaneous (SAT), visceral (VAT), and intermuscular (IMAT) adipose tissue by whole‐body MRI before surgery and at 12 months and 24 months post‐surgery in a subset of participants of the Longitudinal Assessment of Bariatric Surgery‐2. Methods From 0 to 12 months, n = 20 females and 3 males; from 12 to 24 months, n = 42 females and 7 males. Paired t‐tests and GLM repeated measures examined changes in TAT, SAT, VAT, and IMAT at 12 and 24 months, with sex and age as covariates. Results Changes from 0 to 12 months included weight (−41.9 ± 12.1 kg; −36%), TAT (−33.5 ± 9.6 kg; −56%), SAT (−29.2 ± 8.2 kg; −55%), VAT (−3.3 ± 1.6 kg; −73%), and IMAT (−0.99 ± 0.68 kg; −50%), all P < 0.001. In females, from 12 to 24 months, despite relative weight stability (−1.8 ± 6.5 kg, −2%; P = 0.085), VAT (−0.5 ± 0.7 kg; −30%; P < 0.001) and IMAT (−0.2 ± 0.4 kg; −14%; P = 0.012) decreased further. In males, from 12 to 24 months, weight increased (5.1 ± 5.2 kg; 6%; P = 0.04) with no significant changes in TAT or sub‐depots. Conclusions Bariatric surgery continues to induce favorable changes in body composition, i.e., persistent adipose tissue loss at 24 months in the absence of further significant weight loss.