UNIVERSI
TÄ
TS-
BIBLIOTHEK
P
ADERBORN
Anmelden
Menü
Menü
Start
Hilfe
Blog
Weitere Dienste
Neuerwerbungslisten
Fachsystematik Bücher
Erwerbungsvorschlag
Bestellung aus dem Magazin
Fernleihe
Einstellungen
Sprache
Deutsch
Deutsch
Englisch
Farbschema
Hell
Dunkel
Automatisch
Sie befinden Sich nicht im Netzwerk der Universität Paderborn. Der Zugriff auf elektronische Ressourcen ist
gegebenenfalls
nur via VPN oder Shibboleth (DFN-AAI) möglich.
mehr Informationen...
Universitätsbibliothek
Katalog
Suche
Details
Zur Ergebnisliste
Ergebnis 23 von 209
Datensatz exportieren als...
BibTeX
Corticosteroid use and risk of orofacial clefts
Birth defects research. A Clinical and molecular teratology, 2014-06, Vol.100 (6), p.499-506
Skuladottir, Hildur
Wilcox, Allen J.
Ma, Chen
Lammer, Edward J.
Rasmussen, Sonja A.
Werler, Martha M.
Shaw, Gary M.
Carmichael, Suzan L.
2014
Details
Autor(en) / Beteiligte
Skuladottir, Hildur
Wilcox, Allen J.
Ma, Chen
Lammer, Edward J.
Rasmussen, Sonja A.
Werler, Martha M.
Shaw, Gary M.
Carmichael, Suzan L.
Titel
Corticosteroid use and risk of orofacial clefts
Ist Teil von
Birth defects research. A Clinical and molecular teratology, 2014-06, Vol.100 (6), p.499-506
Ort / Verlag
United States: Blackwell Publishing Ltd
Erscheinungsjahr
2014
Link zum Volltext
Quelle
Wiley Online Library Journals Frontfile Complete
Beschreibungen/Notizen
Background Maternal use of corticosteroids during early pregnancy has been inconsistently associated with orofacial clefts in the offspring. A previous report from the National Birth Defect Prevention Study (NBDPS), using data from 1997 to 2002, found an association with cleft lip and palate (odds ratio, 1.7; 95% confidence interval [CI], 1.1–2.6), but not cleft palate only (odds ratio, 0.5, 95%CI, 0.2–1.3). From 2003 to 2009, the study population more than doubled in size, and our objective was to assess this association in the more recent data. Methods The NBDPS is an ongoing multi‐state population‐based case‐control study of birth defects, with ascertainment of cases and controls born since 1997. We assessed the association of corticosteroids and orofacial clefts using data from 2372 cleft cases and 5922 controls born from 2003 to 2009. Maternal corticosteroid exposure was based on telephone interviews. Results The overall association of corticosteroids and cleft lip and palate in the new data was 1.0 (95% CI, 0.7–1.4). There was little evidence of associations between specific corticosteroid components or timing and clefts. Conclusion In contrast to the 1997 to 2002 data from the NBDPS, the 2003 to 2009 data show no association between maternal corticosteroid use and cleft lip and palate in the offspring. Birth Defects Research (Part A) 100:499–506, 2014. © 2014 The Authors Birth Defects Research Part A: Clinical and Molecular Teratology Published by Wiley Periodicals, Inc.
Sprache
Englisch
Identifikatoren
ISSN: 1542-0752
eISSN: 1542-0760
DOI: 10.1002/bdra.23248
Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4283705
Format
–
Schlagworte
Adrenal Cortex Hormones - administration & dosage
,
African Continental Ancestry Group
,
birth defects
,
Case-Control Studies
,
Cleft Lip - epidemiology
,
Cleft Lip - ethnology
,
cleft lip and palate
,
Cleft Palate - epidemiology
,
Cleft Palate - ethnology
,
corticosteroids
,
European Continental Ancestry Group
,
Female
,
Hispanic Americans
,
Humans
,
Infant, Newborn
,
Maternal Exposure - statistics & numerical data
,
Odds Ratio
,
Original s
,
orofacial clefts
,
Pregnancy
,
Risk Factors
,
Surveys and Questionnaires
,
United States - epidemiology
Weiterführende Literatur
Empfehlungen zum selben Thema automatisch vorgeschlagen von
bX