Advanced materials (Weinheim), 2013-10, Vol.25 (38), p.5477-5482
2013
Details
- Autor(en) / Beteiligte
- Titel
- Axonal Alignment and Enhanced Neuronal Differentiation of Neural Stem Cells on Graphene-Nanoparticle Hybrid Structures
- Ist Teil von
- Advanced materials (Weinheim), 2013-10, Vol.25 (38), p.5477-5482
- Ort / Verlag
- Weinheim: WILEY-VCH Verlag
- Erscheinungsjahr
- 2013
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Human neural stem cells (hNSCs) cultured on graphene‐nanoparticle hybrid structures show a unique behavior wherein the axons from the differentiating hNSCs show enhanced growth and alignment. We show that the axonal alignment is primarily due to the presence of graphene and the underlying nanoparticle monolayer causes enhanced neuronal differentiation of the hNSCs, thus having great implications of these hybrid‐nanostructures for neuro‐regenerative medicine.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0935-9648eISSN: 1521-4095DOI: 10.1002/adma.201302219Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4189106
- Format
- –
- Schlagworte
- axonal alignment, Axons - drug effects, Biocompatible Materials - chemistry, Biocompatible Materials - pharmacology, Cell Differentiation - drug effects, Cell Proliferation - drug effects, graphene-coated nanostructures, Graphite - chemistry, Graphite - pharmacology, Humans, Nanoparticles, neural stem cells, Neural Stem Cells - cytology, Neural Stem Cells - drug effects, Oxides - chemistry, Silicon Dioxide - chemistry, stem cell differentiation