Journal of clinical microbiology, 2014-10, Vol.52 (10), p.3805-3807
2014
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Details
- Autor(en) / Beteiligte
- Titel
- Evaluation of the nanosphere Verigene BC-GN assay for direct identification of gram-negative bacilli and antibiotic resistance markers from positive blood cultures and potential impact for more-rapid antibiotic interventions
- Ist Teil von
- Journal of clinical microbiology, 2014-10, Vol.52 (10), p.3805-3807
- Ort / Verlag
- United States: American Society for Microbiology
- Erscheinungsjahr
- 2014
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- The Verigene BC-GN assay correctly identified all 51 Gram-negative bacilli (GNB) from positive blood cultures and all 14 carbapenemase enzymes tested. The assay gave organism identification (ID) results an average of 24 h faster compared to conventional identifications. Medical management could have been modified for 31.8% of patients an average 33 h sooner. In conclusion, the BC-GN assay is a very accurate, rapid assay which would allow for more-immediate medical management decisions in patients with bacteremia from GNB.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0095-1137eISSN: 1098-660XDOI: 10.1128/JCM.01537-14Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4187775
- Format
- –
- Schlagworte
- Anti-Bacterial Agents - pharmacology, Anti-Bacterial Agents - therapeutic use, Bacteremia - diagnosis, Bacteremia - drug therapy, Bacteremia - microbiology, Bacteriology, Blood - microbiology, Drug Resistance, Bacterial, Genetic Markers, Gram-Negative Bacteria - drug effects, Gram-Negative Bacteria - isolation & purification, Gram-Negative Bacterial Infections - diagnosis, Gram-Negative Bacterial Infections - drug therapy, Gram-Negative Bacterial Infections - microbiology, Humans, Molecular Diagnostic Techniques - methods, Nanospheres, Retrospective Studies, Time Factors