Details

Autor(en) / Beteiligte

• FENG ZHOU
• QIBING LIN
• WEIWEI MA
• HE GAO
• JUN CHEN
• CHAO YANG
• DAN WANG
• JUNJIE TAN
• XIN ZHANG
• XIUPING GUO
• JIULIN WANG
• LING JIANG
• LIHONG ZHU
• XI LIU
• WEIQI CHEN
• JINFANG CHU
• CUNYU YAN
• UENO, Kotomi
• ITO, Shinsaku
• ASAMI, Tadao
• ZHIJUN CHENG
• JIE WANG
• CAILIN LEI
• YULONG REN
• HUQU ZHAI
• CHUANYIN WU
• HAIYANG WANG
• NING ZHENG
• JIANMIN WAN
• KUNNENG ZHOU
• SHABEK, Nitzan
• FUQING WU
• HAIBIN MAO
• WEI DONG
• LU GAN

Titel

D14-SCFD3-dependent degradation of D53 regulates strigolactone signalling

Ist Teil von

• Nature (London), 2013-12, Vol.504 (7480), p.406-410

Ort / Verlag

London: Nature Publishing Group

Erscheinungsjahr

2013

Link zum Volltext

Quelle

EBSCOhost Psychology and Behavioral Sciences Collection

Beschreibungen/Notizen

• Strigolactones (SLs) are a new class of carotenoid-derived phytohormones essential for developmental processes shaping plant architecture and interactions with parasitic weeds and symbiotic arbuscular mycorrhizal fungi. Despite the rapid progress in elucidating the SL biosynthetic pathway, the perception and signaling mechanisms of SL remain poorly understood. Here we show that DWARF53 (D53) acts as a repressor of SL signaling and SLs induce its degradation. We found that the rice d53 mutant, which produces an exaggerated number of tillers compared to wild type plants, is caused by a gain-of-function mutation and is insensitive to exogenous SL treatment. The D53 gene product shares predicted features with the class I Clp ATPase proteins and can form a complex with the α/β hydrolase protein DWARF14 (D14) and the F-box protein DWARF3 (D3), two previously identified signaling components potentially responsible for SL perception. We demonstrate that, in a D14- and D3-dependent manner, SLs induce D53 degradation by the proteasome and abrogate its activity in promoting axillary bud outgrowth. Our combined genetic and biochemical data reveal that D53 acts as a repressor of the SL signaling pathway, whose hormone-induced degradation represents a key molecular link between SL perception and responses.