Acta pharmacologica Sinica, 2013-06, Vol.34 (6), p.747-754
2013
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Details
- Autor(en) / Beteiligte
- Titel
- Mesenchymal stem cells： a new trend for cell therapy
- Ist Teil von
- Acta pharmacologica Sinica, 2013-06, Vol.34 (6), p.747-754
- Ort / Verlag
- United States: Nature Publishing Group
- Erscheinungsjahr
- 2013
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Mesenchymal stem cells （MSCs）, the major stem cells for cell therapy, have been used in the clinic for approximately 10 years. From animal models to clinical trials, MSCs have afforded promise in the treatment of numerous diseases, mainly tissue injury and immune disorders. In this review, we summarize the recent opinions on methods, timing and cell sources for MSC administration in clinical applications, and provide an overview of mechanisms that are significant in MSC-mediated therapies. Although MSCs for cell therapy have been shown to be safe and effective, there are still challenges that need to be tackled before their wide application in the clinic.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1671-4083eISSN: 1745-7254DOI: 10.1038/aps.2013.50Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_4002895
- Format
- –
- Schlagworte
- Animals, Clinical Trials as Topic, Disease Models, Animal, Humans, Immune System Diseases - physiopathology, Immune System Diseases - therapy, Mesenchymal Stem Cell Transplantation - methods, Mesenchymal Stromal Cells - metabolism, MSCs, Review, Time Factors, Wounds and Injuries - physiopathology, Wounds and Injuries - therapy, 临床应用, 临床试验, 免疫系统, 动物模型, 组织损伤, 细胞治疗, 间充质干细胞