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Analytical chemistry (Washington), 2013-12, Vol.85 (23), p.11545-11552
2013
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Tunable-Delay Shunts for Paper Microfluidic Devices
- Ist Teil von
- Analytical chemistry (Washington), 2013-12, Vol.85 (23), p.11545-11552
- Ort / Verlag
- United States: American Chemical Society
- Erscheinungsjahr
- 2013
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- We demonstrate a novel method for controlling fluid flow in paper-based devices. The method delays fluid progress through a porous channel by diverting fluid into an absorbent pad-based shunt placed into contact with the channel. Parameters to control the delay include the length and the thickness of the shunt. Using this method, reproducible delays ranging from 3 to 20 min were achieved. A simple electrical circuit model was presented and used to predict the delays in a system. Results from the model showed good agreement with experimental observations. Finally, the shunts were used for the sequential delivery of fluids to a detection zone in a point-of-care compatible folding card device using biochemical reagents for the amplified detection of the malaria protein PfHRP2.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0003-2700eISSN: 1520-6882DOI: 10.1021/ac4030939Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3950207
- Format
- –
- Schlagworte
- Analytical chemistry, Biochemistry, Bypasses, Circuits, Collodion - chemistry, Computational fluid dynamics, Delay, Devices, Fluid flow, Fluids, Mathematical models, Microfluidic Analytical Techniques - instrumentation, Microfluidic Analytical Techniques - methods, Shunts, Time Factors