Details

Autor(en) / Beteiligte

• DONATO, GIUSEPPE
• CONFORTI, FRANCESCO
• ALLEGRA, EUGENIA

Titel

A rare case of primary nodal hemangioendothelioma

Ist Teil von

• Oncology letters, 2013-12, Vol.6 (6), p.1759-1761

Ort / Verlag

Greece: D.A. Spandidos

Erscheinungsjahr

2013

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Primary vascular tumors of the lymph nodes other than Kaposi's sarcoma are rare. The present study describes the case of a primary hemangioendothelioma in a cervical lymph node in a patient treated for a carcinoma of the large bowel. Microscopically, the structure of the lymph node was completely substituted by tumoral proliferation, with an architectural pattern consisting of anastomosing vascular channels, a number of which contained papillary projections or a tuft-like structure. This study demonstrates the potential diagnostic errors and hypothesizes the pathogenesis of this type of lesion; a vascular endothelial growth factor (VEGF)/VEGF receptor-3 (VEGFR-3) autocrine loop may be activated.