Details

Autor(en) / Beteiligte

• Jasinska, Anna J.
• Schmitt, Christopher A.
• Service, Susan K.
• Cantor, Rita M.
• Dewar, Ken
• Jentsch, James D.
• Kaplan, Jay R.
• Turner, Trudy R.
• Warren, Wesley C.
• Weinstock, George M.
• Woods, Roger P.
• Freimer, Nelson B.

Titel

Systems Biology of the Vervet Monkey

Ist Teil von

• ILAR journal, 2013-01, Vol.54 (2), p.122-143

Ort / Verlag

England: Oxford University Press

Erscheinungsjahr

2013

Quelle

MEDLINE

Beschreibungen/Notizen

• Nonhuman primates (NHP) provide crucial biomedical model systems intermediate between rodents and humans. The vervet monkey (also called the African green monkey) is a widely used NHP model that has unique value for genetic and genomic investigations of traits relevant to human diseases. This article describes the phylogeny and population history of the vervet monkey and summarizes the use of both captive and wild vervet monkeys in biomedical research. It also discusses the effort of an international collaboration to develop the vervet monkey as the most comprehensively phenotypically and genomically characterized NHP, a process that will enable the scientific community to employ this model for systems biology investigations.