Details

Autor(en) / Beteiligte

• Bowden, Bruce F.
• Cusack, Bernard J.
• Dangel, Alissa

Titel

13-Epi-9-deacetoxyxenicin, a Cytotoxic Diterpene from the Soft Coral Asterospicularia laurae (Alcyonacea)

Ist Teil von

• Marine drugs, 2003-11, Vol.1 (4), p.18-26

Ort / Verlag

Molecular Diversity Preservation International (MDPI)

Erscheinungsjahr

2003

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• An investigation of the soft coral Asterospicularia laurae collected on the Great Barrier Reef, Australia, afforded the cytotoxic diterpene 13- epi -9-deacetoxyxenicin ( 1 ) in addition to the known metabolites 13- epi -9-deacetylxenicin ( 2 ) and gorgosterol. 13- Epi -9-deacetoxyxenicin readily underwent an autoxidation reaction in solution to afford a single product, the hydroperoxide 3 . Structures, stereochemistry, and NMR assignments were established by high resolution NMR spectroscopy and by comparison with published data for known compounds.