Details

Autor(en) / Beteiligte

• Gerard, Baudouin
• Lee, Maurice D
• Dandapani, Sivaraman
• Duvall, Jeremy R
• Fitzgerald, Mark E
• Kesavan, Sarathy
• Lowe, Jason T
• Marié, Jean-Charles
• Pandya, Bhaumik A
• Suh, Byung-Chul
• O’Shea, Morgan Welzel
• Dombrowski, Michael
• Hamann, Diane
• Lemercier, Berenice
• Murillo, Tiffanie
• Akella, Lakshmi B
• Foley, Michael A
• Marcaurelle, Lisa A

Titel

Synthesis of Stereochemically and Skeletally Diverse Fused Ring Systems from Functionalized C‑Glycosides

Ist Teil von

• Journal of organic chemistry, 2013-06, Vol.78 (11), p.5160-5171

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2013

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• A diversity-oriented synthesis (DOS) strategy was developed for the synthesis of stereochemically diverse fused-ring systems containing a pyran moiety. Each scaffold contains an amine and methyl ester for further diversification via amine capping and amide coupling. Scaffold diversity was evaluated in comparison to previously prepared scaffolds by a shape-based principal moments of inertia (PMI) analysis.