Details

Autor(en) / Beteiligte

• Lin, Audrie
• Arnold, Benjamin F
• Afreen, Sadia
• Goto, Rie
• Huda, Tarique Mohammad Nurul
• Haque, Rashidul
• Raqib, Rubhana
• Unicomb, Leanne
• Ahmed, Tahmeed
• Colford, John M
• Luby, Stephen P

Titel

Household environmental conditions are associated with enteropathy and impaired growth in rural Bangladesh

Ist Teil von

• The American journal of tropical medicine and hygiene, 2013-07, Vol.89 (1), p.130-137

Ort / Verlag

United States: The American Society of Tropical Medicine and Hygiene

Erscheinungsjahr

2013

Link zum Volltext

Quelle

MEDLINE

Beschreibungen/Notizen

• We assessed the relationship of fecal environmental contamination and environmental enteropathy. We compared markers of environmental enteropathy, parasite burden, and growth in 119 Bangladeshi children (≤ 48 months of age) across rural Bangladesh living in different levels of household environmental cleanliness defined by objective indicators of water quality and sanitary and hand-washing infrastructure. Adjusted for potential confounding characteristics, children from clean households had 0.54 SDs (95% confidence interval [CI] = 0.06, 1.01) higher height-for-age z scores (HAZs), 0.32 SDs (95% CI = -0.72, 0.08) lower lactulose:mannitol (L:M) ratios in urine, and 0.24 SDs (95% CI = -0.63, 0.16) lower immunoglobulin G endotoxin core antibody (IgG EndoCAb) titers than children from contaminated households. After adjusting for age and sex, a 1-unit increase in the ln L:M was associated with a 0.33 SDs decrease in HAZ (95% CI = -0.62, -0.05). These results are consistent with the hypothesis that environmental contamination causes growth faltering mediated through environmental enteropathy.