Details

Autor(en) / Beteiligte

• Marchbanks, Tiffany L.
• Bhattarai, Achuyt
• Fagan, Ryan P.
• Ostroff, Stephen
• Sodha, Samir V.
• Moll, Mària E.
• Lee, Bruce Y.
• Chang, Chung-Chou H.
• Ennis, Brent
• Britz, Phyllis
• Fiore, Anthony
• Nguyen, Michael
• Palekar, Rakhee
• Archer, W. Roodly
• Gift, Thomas L.
• Leap, Rebecca
• Nygren, Benjamin L.
• Cauchemez, Simon
• Angulo, Frederick J.
• Swerdlow, David

Titel

An Outbreak of 2009 Pandemic Influenza A (H1N1) Virus Infection in an Elementary School in Pennsylvania

Ist Teil von

• Clinical infectious diseases, 2011-01, Vol.52 (suppl_1), p.S154-S160

Ort / Verlag

United States: University of Chicago Press

Erscheinungsjahr

2011

Quelle

Oxford Journals 2020 Medicine

Beschreibungen/Notizen

• In May 2009, one of the earliest outbreaks of 2009 pandemic influenza A virus (pH1N1) infection resulted in the closure of a semi-rural Pennsylvania elementary school. Two sequential telephone surveys were administered to 1345 students (85% of the students enrolled in the school) and household members in 313 households to collect data on influenza-like illness (ILI). A total of 167 persons (12.4%) among those in the surveyed households, including 93 (24.0%) of the School A students, reported ILI. Students were 3.1 times more likely than were other household members to develop ILI (95% confidence interval [CI], 2.3—4.1). Fourth-grade students were more likely to be affected than were students in other grades (relative risk, 2.2; 95% CI, 1.2—3.9). pH1N1 was confirmed in 26 (72.2%) of the individuals tested by real-time reverse-transcriptase polymerase chain reaction. The outbreak did not resume upon the reopening of the school after the 7-day closure. This investigation found that pH1N1 outbreaks at schools can have substantial attack rates; however, grades and classrooms are affected variably. Additioanl study is warranted to determine the effectiveness of school closure during outbreaks.