Angewandte Chemie (International ed.), 2013-05, Vol.52 (20), p.5377-5381
2013
Details
- Autor(en) / Beteiligte
- Titel
- Dual Responsive, Stabilized Nanoparticles for Efficient In Vivo Plasmid Delivery
- Ist Teil von
- Angewandte Chemie (International ed.), 2013-05, Vol.52 (20), p.5377-5381
- Ort / Verlag
- Weinheim: WILEY-VCH Verlag
- Erscheinungsjahr
- 2013
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- A small case of love and hate: A block‐statistical copolymer combining reversible hydrophobization and statistical hydrophilization allows the preparation of pH value‐ and reduction‐responsive nanoparticles (polyplexes) for efficient in vivo plasmid delivery.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1433-7851eISSN: 1521-3773DOI: 10.1002/anie.201301896Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3738056
- Format
- –
- Schlagworte
- copolymers, DNA nanoparticles, Drug Carriers - chemistry, Drug Stability, Endocytosis, Endosomes - metabolism, gene transfection, Gene Transfer Techniques, HeLa Cells, Humans, hydrophilization, Hydrophobic and Hydrophilic Interactions, hydrophobization, Microscopy, Electron, Transmission, Nanoparticles - chemistry, Plasmids - administration & dosage, Plasmids - genetics, Polymers - chemistry, RNA, Small Interfering - administration & dosage, RNA, Small Interfering - genetics, Surface Properties, Transfection