Details

Autor(en) / Beteiligte

• Lei, Guowei
• Chen, Mingkuan
• Li, Hua
• Niu, Jun-Ling
• Wu, Shuxian
• Mao, Liming
• Lu, Ailing
• Wang, Hongbin
• Chen, Wei
• Xu, Bin
• Leng, Qibin
• Xu, Cunshuan
• Yang, Guiwen
• An, Liguo
• Zhu, Li-Ping
• Meng, Guangxun

Titel

Biofilm from a clinical strain of Cryptococcus neoformans activates the NLRP3 inflammasome

Ist Teil von

• Cell research, 2013-07, Vol.23 (7), p.965-968

Ort / Verlag

London: Nature Publishing Group UK

Erscheinungsjahr

2013

Quelle

EZB-FREE-00999 freely available EZB journals

Beschreibungen/Notizen

• Dear Editor, Many opportunistic fungi are devastating pathogens that cause lethal infection. Cryptococcus neoformans （C. neoformans） is such a fungus that mainly infects im- munocompromised hosts such as AIDS patients as well as organ transplant recipients, and causes cryptococco- sis including life-threatening meningoencephalitis [1]. Cryptococcal meningitis affects about a million AIDS patients and causes 625 000 deaths in the world yearly [2]. The disease also occurs in apparently immunocompetent individuals [3]. However, host immune responses to C. neoformans are not well studied.