Details

Autor(en) / Beteiligte

• Tas, Faruk
• Keskin, Serkan
• Pasmatzi, E.
• Chao, S.-C.
• Tuzun, Y.
• Val-Bernal, J. F.

Titel

Mucosal Melanoma in the Head and Neck Region: Different Clinical Features and Same Outcome to Cutaneous Melanoma

Ist Teil von

• ISRN Dermatology, 2013, Vol.2013, p.586915-5

Ort / Verlag

Egypt: Hindawi Publishing Corporation

Erscheinungsjahr

2013

Quelle

Free E-Journal (出版社公開部分のみ）

Beschreibungen/Notizen

• Mucosal melanoma (MM) in the head and neck (H&N) is relatively rare and behaves in distinct pattern from cutaneous melanoma (CM). We performed this study to define clinical characteristics and outcomes of patients and emphasize MM differences from CM. Forty-one patients with MM located in H&N were assessed. 94 CM patients originated from H&N region were also used for comparison. Patients had oral cavity (51%) and sinonasal location (49%).The median age was 60 years and gender distribution was equal. Thirty-two (78%) patients had localized stage, four (10%) patients had regional lymph node metastasis, and five (12%) patients had distant metastasis. The 1- and 5-year overall survival rates were 81% and 58%, respectively. Outcomes were similar between sinonasal and oral cavity patients (P=0.67). Advanced disease was the significant prognostic factor for outcome (P=0.03). MM patients are older (P=0.008) and more diagnosed as a localized disease patients at presentation than those with CM (P=0.06). Overall survival rates were identical in patients with MM and CM (P=0.53). In conclusion, despite different clinical features, outcome was identical in patients with MM and CM located in the H&N region.