Details

Autor(en) / Beteiligte

• Cichocka-Jarosz, Ewa
• Brzyski, Piotr
• Swiebocka, Ewa
• Lange, Joanna
• Tobiasz-Adamczyk, Beata
• Lis, Grzegorz
• Jedynak-Wąsowicz, Urszula
• Kulus, Marek
• Kaczmarski, Maciej
• Małaczyńska, Teresa
• Klajna-Kraluk, Barbara
• Bręborowicz, Anna
• Kycler, Zdzisława
• Pietrzyk, Jacek J

Titel

Health-related quality of life in Polish adolescents with Hymenoptera venom allergy treated with venom immunotherapy

Ist Teil von

• Archives of medical science, 2012-12, Vol.8 (6), p.1076-1082

Ort / Verlag

Poland: Termedia Publishing House

Erscheinungsjahr

2012

Link zum Volltext

Quelle

EZB Electronic Journals Library

Beschreibungen/Notizen

• Venom allergy, though rare, may seriously influence health-related quality of life (HRQoL). There is a paucity of research on HRQoL of adolescents and young adults with Hymenoptera venom allergy. The aim was to assess the level of HRQoL and to evaluate its independent predictors in Polish adolescents and young adults treated with venom immunotherapy. A multicenter cross-sectional study based on the Vespid Allergy Quality of Life Questionnaire (VQLQ) adapted for Polish adolescents was used. The study sample included 87 patients (14-21 years) studied at different stages of venom immunotherapy (VIT). Statistical analysis was done with multivariate linear regression. Anxiety level was higher in patients with 4(th) grade of Mueller's classification (anaphylactic shock) than in those with 3(rd) grade (B = 0.84, 95% CI = 0.07-1.61, p = 0.03). Caution increased along with an increase of anxiety of adolescents treated with VIT (B = 0.54, 95% CI = 0.39-0.68, p < 0.01). Level of limitations increased with increasing caution of adolescents (B = 0.63, 95% CI = 0.35-0.91, p < 0.01). Discomfort increased along with a rise of caution of patients (B = 0.38, 95% CI = 0.22-0.55, p < 0.01). Similarly, it increased with an increase of their feeling of limitations (B = 0.37, 95% CI = 0.23-0.51, p < 0.01). The level of discomfort in adolescents treated with VIT was lower in those who were treated with conventional protocol in comparison to those treated with rush or ultra-rush ones (B = -0.47, 95% CI = -0.90 - -0.03, p = 0.04). Severity of anaphylactic reaction is an independent determinant of anxiety level in adolescents treated with VIT. The VIT protocol affects HRQoL of treated patients.