Details

Autor(en) / Beteiligte

• Fan, Song
• Tang, Qiong-Lan
• Lin, Ying-Jin
• Chen, Wei-Liang
• Li, Jin-Song
• Huang, Zhi-Quan
• Yang, Zhao-Hui
• Wang, You-Yuan
• Zhang, Da-Ming
• Wang, Hui-Jing
• Dias-Ribeiro, Eduardo
• Cai, Qiang
• Wang, Lei

Titel

A review of clinical and histological parameters associated with contralateral neck metastases in oral squamous cell carcinoma

Ist Teil von

• International journal of oral science, 2011-10, Vol.3 (4), p.180-191

Ort / Verlag

India: Springer Nature B.V

Erscheinungsjahr

2011

Quelle

MEDLINE

Beschreibungen/Notizen

• Oral squamous cell carcinoma （OSCC） has a high incidence of cervical micrometastases and sometimes metastasizes contralaterally because of the rich lymphatic intercommunications relative to submucosal plexus of oral cavity that freely communicate across the midline, and it can facilitate the spread of neoplastic cells to any area of the neck consequently. Clinical and histopathologic factors continue to provide predictive information to contralateral neck metastases （CLNM） in OSCC, which determine prophylactic and adjuvant treatments for an individual patient. This review describes the predictive value of clinical-histopathologic factors, which relate to primary tumor and cervical lymph nodes, and surgical dissection and adjuvant treatments. In addition, the indications for elective contralateral neck dissection and adjuvant radiotherapy （aRT） and strategies for follow-up are offered, which is strongly focused by clinicians to prevent later CLNM and poor prognosis subsequently.