Nucleic acids research, 1986-01, Vol.14 (1), p.75-86
1986
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Details
- Autor(en) / Beteiligte
- Titel
- sequence analysis system encompassing rules for DNA helical distortion
- Ist Teil von
- Nucleic acids research, 1986-01, Vol.14 (1), p.75-86
- Ort / Verlag
- Oxford: Oxford University Press
- Erscheinungsjahr
- 1986
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Recently, it has been shown by Calladine (1982) and Dickerson (1983) that DNA distortions due to steric clashes between opposing purines and pyrimidines can be quantitated based upon four sum functions. The distortions involve helical twist, roll, torsion angle variations and propellar twist. It is the contention of the authors that these perturbations in structure act as information carriers for various external interactions. This paper describes a system that incorporates these four rules and various other functions that permit the systematic interactive exploration for significant patterns as a consequence of these steric clashes.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0305-1048eISSN: 1362-4962DOI: 10.1093/nar/14.1.75Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_339357
- Format
- –
- Schlagworte
- Analytical, structural and metabolic biochemistry, Applied sciences, Base Sequence, Biological and medical sciences, calladine-dickerson rules, computer analysis, computer software, Computers, DNA, DNA - analysis, DNA conformation, Dna, deoxyribonucleoproteins, Exact sciences and technology, Fundamental and applied biological sciences. Psychology, Nucleic Acid Conformation, Nucleic acids, nucleotide sequences, Other techniques and industries, Software, steric clashes