Details

Autor(en) / Beteiligte

• Dunn, Gavin P
• Rinne, Mikael L
• Wykosky, Jill
• Genovese, Giannicola
• Quayle, Steven N
• Dunn, Ian F
• Agarwalla, Pankaj K
• Chheda, Milan G
• Campos, Benito
• Wang, Alan
• Brennan, Cameron
• Ligon, Keith L
• Furnari, Frank
• Cavenee, Webster K
• Depinho, Ronald A
• Chin, Lynda
• Hahn, William C

Titel

Emerging insights into the molecular and cellular basis of glioblastoma

Ist Teil von

• Genes & development, 2012-04, Vol.26 (8), p.756-784

Ort / Verlag

United States: Cold Spring Harbor Laboratory Press

Erscheinungsjahr

2012

Link zum Volltext

Quelle

Electronic Journals Library

Beschreibungen/Notizen

• Glioblastoma is both the most common and lethal primary malignant brain tumor. Extensive multiplatform genomic characterization has provided a higher-resolution picture of the molecular alterations underlying this disease. These studies provide the emerging view that "glioblastoma" represents several histologically similar yet molecularly heterogeneous diseases, which influences taxonomic classification systems, prognosis, and therapeutic decisions.