Nature neuroscience, 2011-10, Vol.14 (10), p.1250-1252
2011
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Details
- Autor(en) / Beteiligte
- Titel
- Differential roles of human striatum and amygdala in associative learning
- Ist Teil von
- Nature neuroscience, 2011-10, Vol.14 (10), p.1250-1252
- Ort / Verlag
- United States: Nature Publishing Group
- Erscheinungsjahr
- 2011
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Although the human amygdala and striatum have both been implicated in associative learning, only the striatum's contribution has been consistently computationally characterized. Using a reversal learning task, we found that amygdala blood oxygen level-dependent activity tracked associability as estimated by a computational model, and dissociated it from the striatal representation of reinforcement prediction error. These results extend the computational learning approach from striatum to amygdala, demonstrating their complementary roles in aversive learning.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1097-6256eISSN: 1546-1726DOI: 10.1038/nn.2904Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3268261
- Format
- –
- Schlagworte
- Adolescent, Adult, Amygdala (Brain), Amygdala - blood supply, Amygdala - physiology, Animals, Association Learning - physiology, Brain Mapping, Computer Simulation, Conditioning, Classical - physiology, Corpus striatum, Corpus Striatum - blood supply, Corpus Striatum - physiology, Emotions - physiology, Female, Galvanic Skin Response - physiology, Health aspects, Humans, Image Processing, Computer-Assisted - methods, Likelihood Functions, Magnetic Resonance Imaging - methods, Male, Neurosciences, Oxygen - blood, Pattern Recognition, Visual - physiology, Physical Stimulation - methods, Physiological aspects, Roles, Time Factors, Young Adult