Current opinion in immunology, 2011-10, Vol.23 (5), p.583-590
2011
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- IFN-λs
- Ist Teil von
- Current opinion in immunology, 2011-10, Vol.23 (5), p.583-590
- Ort / Verlag
- England: Elsevier Ltd
- Erscheinungsjahr
- 2011
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Highlights ► The interferon (IFN) family was recently expanded with the discovery of type III IFNs. ► Type III IFNs or IFN-λs, also known as IL-28/29, are directly induced by viral infection. ► IFN-λs, together with type I IFNs, function as early mediators of the innate antiviral response. ► IFN-λs engage a specific receptor complex to induce antiviral state in cells. ► IFN-λs possess unique biological activities in and beyond innate antiviral immunity.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0952-7915eISSN: 1879-0372DOI: 10.1016/j.coi.2011.07.007Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3196341
- Format
- –
- Schlagworte
- Allergy and Immunology, Animals, Chromosomes, Human, Pair 19 - chemistry, Chromosomes, Human, Pair 19 - immunology, Exons, Gene Expression Regulation - immunology, Humans, Immunity, Innate, Interferon-alpha - genetics, Interferon-alpha - immunology, Interferon-alpha - metabolism, Interferon-beta - genetics, Interferon-beta - immunology, Interferon-beta - metabolism, Interferons, Interleukins - genetics, Interleukins - immunology, Interleukins - metabolism, Intestinal Mucosa - immunology, Intestinal Mucosa - virology, Introns, Mice, Multigene Family, Organ Specificity, Receptors, Interferon - genetics, Receptors, Interferon - immunology, Receptors, Interferon - metabolism, Signal Transduction - immunology, Virus Diseases - immunology, Virus Diseases - virology, Viruses - immunology