Epilepsy research, 2011-09, Vol.96 (1), p.116-122
2011
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Details
- Autor(en) / Beteiligte
- Titel
- A novel implanted device to wirelessly record and analyze continuous intracranial canine EEG
- Ist Teil von
- Epilepsy research, 2011-09, Vol.96 (1), p.116-122
- Ort / Verlag
- Kidlington: Elsevier B.V
- Erscheinungsjahr
- 2011
- Quelle
- Access via ScienceDirect (Elsevier)
- Beschreibungen/Notizen
- Summary We present results from continuous intracranial electroencephalographic (iEEG) monitoring in 6 dogs with naturally occurring epilepsy, a disorder similar to the human condition in its clinical presentation, epidemiology, electrophysiology and response to therapy. Recordings were obtained using a novel implantable device wirelessly linked to an external, portable real-time processing unit. We demonstrate previously uncharacterized intracranial seizure onset patterns in these animals that are strikingly similar in appearance to human partial onset epilepsy. We propose: (1) canine epilepsy as an appropriate model for testing human antiepileptic devices and new approaches to epilepsy surgery, and (2) this new technology as a versatile platform for evaluating seizures and response to therapy in the natural, ambulatory setting.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0920-1211eISSN: 1872-6844DOI: 10.1016/j.eplepsyres.2011.05.011Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3175300
- Format
- –
- Schlagworte
- Algorithms, Animals, Anticonvulsants - pharmacology, Anticonvulsants - therapeutic use, Biological and medical sciences, Canine, Dogs, EEG, Electrodes, Implanted, Electrodiagnosis. Electric activity recording, Electroencephalography - instrumentation, Electroencephalography - methods, Epilepsy - diagnosis, Epilepsy - drug therapy, Epilepsy - physiopathology, Epilepsy - veterinary, Epilepsy device, Female, Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy, Intracranial, Investigative techniques, diagnostic techniques (general aspects), Male, Medical sciences, Monitoring, Physiologic, Nervous system, Nervous system (semeiology, syndromes), Neurology, Telemetry - instrumentation, Telemetry - methods, Wakefulness