Genes & development, 2000-12, Vol.14 (23), p.3024-3036
2000
Volltextzugriff (PDF)
Details
- Autor(en) / Beteiligte
- Titel
- Arabidopsis NAC1 transduces auxin signal downstream of TIR1 to promote lateral root development
- Ist Teil von
- Genes & development, 2000-12, Vol.14 (23), p.3024-3036
- Ort / Verlag
- United States: Cold Spring Harbor Laboratory Press
- Erscheinungsjahr
- 2000
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Auxin plays a key role in lateral root formation, but the signaling pathway for this process is poorly understood. We show here that NAC1, a new member of the NAC family, is induced by auxin and mediates auxin signaling to promote lateral root development. NAC1 is a transcription activator consisting of an N-terminal conserved NAC-domain that binds to DNA and a C-terminal activation domain. This factor activates the expression of two downstream auxin-responsive genes, DBP and AIR3. Transgenic plants expressing sense or antisense NAC1 cDNA show an increase or reduction of lateral roots, respectively. Finally, TIR1-induced lateral root development is blocked by expression of antisense NAC1 cDNA, and NAC1 overexpression can restore lateral root formation in the auxin-response mutant tir1, indicating that NAC1 acts downstream of TIR1.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0890-9369eISSN: 1549-5477DOI: 10.1101/gad.852200Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_317103
- Format
- –
- Schlagworte
- AIR3 gene, Amino Acid Sequence, Arabidopsis, Arabidopsis - genetics, Arabidopsis - growth & development, Arabidopsis - metabolism, Arabidopsis Proteins, Base Sequence, Cotyledon - metabolism, DBP gene, Dimerization, DNA, Complementary, DNA-Binding Proteins - genetics, DNA-Binding Proteins - metabolism, DNA-Binding Proteins - physiology, Gene Expression, Indoleacetic Acids - metabolism, Molecular Sequence Data, NAC1 gene, Oligonucleotides, Antisense, Peptide Synthases - metabolism, Plant Leaves - metabolism, Plant Proteins - genetics, Plant Proteins - metabolism, Plant Proteins - physiology, Plant Roots - growth & development, Plants, Genetically Modified, Protein Structure, Tertiary, Research Paper, Response Elements, Signal Transduction - physiology, SKP Cullin F-Box Protein Ligases, TIR1 gene, Trans-Activators - genetics, Trans-Activators - metabolism, Trans-Activators - physiology, Transcriptional Activation