Details

Autor(en) / Beteiligte

• Bhengsri, Saithip
• Baggett, Henry C
• Jorakate, Possawat
• Kaewpan, Anek
• Prapasiri, Prabda
• Naorat, Sathapana
• Thamthitiwat, Somsak
• Tanwisaid, Kittisak
• Chantra, Somrak
• Salika, Prasert
• Dejsirilert, Surang
• Peruski, Leonard F
• Maloney, Susan A

Titel

Incidence of bacteremic melioidosis in eastern and northeastern Thailand

Ist Teil von

• The American journal of tropical medicine and hygiene, 2011-07, Vol.85 (1), p.117-120

Ort / Verlag

United States: The American Society of Tropical Medicine and Hygiene

Erscheinungsjahr

2011

Quelle

MEDLINE

Beschreibungen/Notizen

• Burkholderia pseudomallei, the causative agent of melioidosis, is endemic in northeastern Thailand. Population-based disease burden estimates are lacking and limited data on melioidosis exist from other regions of the country. Using active, population-based surveillance, we measured the incidence of bacteremic melioidosis in the provinces of Sa Kaeo (eastern Thailand) and Nakhon Phanom (northeastern Thailand) during 2006-2008. The average annual incidence in Sa Kaeo and Nakhon Phanom per 100,000 persons was 4.9 (95% confidence interval [CI] = 3.9-6.1) and 14.9 (95% CI = 13.3-16.6). The respective population mortality rates were 1.9 (95% CI = 1.3-2.8) and 4.4 (95% CI = 3.6-5.3) per 100,000. The case-fatality proportion was 36% among those with known outcome. Our findings document a high incidence and case fatality proportion of bacteremic melioidosis in Thailand, including a region not traditionally considered highly endemic, and have potential implications for clinical management and health policy.