Trends in neurosciences (Regular ed.), 2010-12, Vol.33 (12), p.533-540
2010
Details
- Autor(en) / Beteiligte
- Titel
- Functional localization within the prefrontal cortex: missing the forest for the trees?
- Ist Teil von
- Trends in neurosciences (Regular ed.), 2010-12, Vol.33 (12), p.533-540
- Ort / Verlag
- Amsterdam: Elsevier Ltd
- Erscheinungsjahr
- 2010
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Anatomical and functional studies of the prefrontal cortex (PFC) have identified multiple PFC subregions. We argue that the PFC is involved in cognitive functions exceeding the sum of specific functions attributed to its subregions. These can be revealed either by lesions of the whole PFC, or more specifically by selective disconnection of the PFC from certain types of information (for example, visual) allowing the investigation of PFC function in toto . Recent studies in macaque monkeys using the latter approach lead to a second conclusion: that the PFC, as a whole, could be fundamentally specialized for representing events that are extended in time. The representation of temporally complex events might underlie PFC involvement in general intelligence, decision-making, and executive function.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0166-2236eISSN: 1878-108XDOI: 10.1016/j.tins.2010.08.001Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2997428
- Format
- –
- Schlagworte
- Adaptation, Physiological, Animals, Biological and medical sciences, Brain, Cognition & reasoning, Cognition - physiology, Critical thinking, Decision Making, Electrodiagnosis. Electric activity recording, Fundamental and applied biological sciences. Psychology, Humans, Information processing, Investigative techniques, diagnostic techniques (general aspects), Macaca, Medical sciences, Nervous system, Neurology, Opinion, Prefrontal Cortex - anatomy & histology, Prefrontal Cortex - physiology, Somesthesis and somesthetic pathways (proprioception, exteroception, nociception), interoception, electrolocation. Sensory receptors, Vertebrates: nervous system and sense organs