British journal of cancer, 2010-10, Vol.103 (8), p.1144-1148
2010
Details
- Autor(en) / Beteiligte
- Titel
- MicroRNA in lung cancer
- Ist Teil von
- British journal of cancer, 2010-10, Vol.103 (8), p.1144-1148
- Ort / Verlag
- Basingstoke: Nature Publishing Group
- Erscheinungsjahr
- 2010
- Link zum Volltext
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- MicroRNAs (miRNAs) are small non-protein-coding RNAs that function as endogenous negative gene regulators. Dysfunctions of miRNAs are frequently found in malignancies, including lung cancer. In this review, we summarise the current understanding of miRNAs in lung cancer tumourigenesis, and highlight their potential in overcoming drug resistance, abetting histological sub-classification techniques, and serving as biomarkers for lung cancer risk stratification and outcome prediction.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0007-0920eISSN: 1532-1827DOI: 10.1038/sj.bjc.6605901Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2967070
- Format
- –
- Schlagworte
- Animals, Antineoplastic Combined Chemotherapy Protocols - therapeutic use, Biological and medical sciences, biomarkers, Carcinoma, Non-Small-Cell Lung - diagnosis, Carcinoma, Non-Small-Cell Lung - drug therapy, Carcinoma, Non-Small-Cell Lung - genetics, Carcinoma, Non-Small-Cell Lung - pathology, Drug Delivery Systems - methods, Drug resistance, Humans, Lung cancer, Lung Neoplasms - diagnosis, Lung Neoplasms - drug therapy, Lung Neoplasms - genetics, Lung Neoplasms - pathology, Malignancy, Medical sciences, MicroRNAs - biosynthesis, MicroRNAs - genetics, MicroRNAs - physiology, Minireview, miRNA, Models, Biological, Pneumology, Prognosis, Tumors, Tumors of the respiratory system and mediastinum