Details

Autor(en) / Beteiligte

• Kwok, Sen W
• Fotsing, Joseph R
• Fraser, Rebecca J
• Rodionov, Valentin O
• Fokin, Valery V

Titel

Transition-Metal-Free Catalytic Synthesis of 1,5-Diaryl-1,2,3-triazoles

Ist Teil von

• Organic letters, 2010-10, Vol.12 (19), p.4217-4219

Ort / Verlag

United States: American Chemical Society

Erscheinungsjahr

2010

Quelle

MEDLINE

Beschreibungen/Notizen

• 1,5-Diarylsubstituted 1,2,3-triazoles are formed in high yield from aryl azides and terminal alkynes in DMSO in the presence of catalytic tetraalkylammonium hydroxide. The reaction is experimentally simple, does not require a transition-metal catalyst, and is not sensitive to atmospheric oxygen and moisture.