Details

Autor(en) / Beteiligte

• Vivero, Richard J
• Fan, Kenneth
• Angeli, Simon
• Balkany, Thomas J
• Liu, Xue Z

Titel

Cochlear implantation in common forms of genetic deafness

Ist Teil von

• International journal of pediatric otorhinolaryngology, 2010-10, Vol.74 (10), p.1107-1112

Ort / Verlag

Ireland: Elsevier Ireland Ltd

Erscheinungsjahr

2010

Quelle

Access via ScienceDirect (Elsevier)

Beschreibungen/Notizen

• Abstract Genetic factors are among the main etiologies of severe to profound hearing loss and may play an important role in cochlear implantation (CI) outcomes. While genes for common forms of deafness have been cloned, efforts to correlate the functional outcome of CIs with a genetic form of deafness carried by the patient have been largely anecdotal to date. It has been suggested that the differences in auditory performance may be explained by differences in the number of surviving spiral ganglion cells, etiology of hearing loss, and other factors. Knowledge of the specific loci and mutations involved in patients who receive cochlear implants may elucidate other factors related to CI performance. In this review article, current knowledge of cochlear implants for hereditary hearing loss will be discussed with an emphasis on relevant clinical genotype–phenotype correlations.