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Advances in dental research, 2009, Vol.21 (1), p.17-20
Ort / Verlag
United States: SAGE Publications
Erscheinungsjahr
2009
Quelle
MEDLINE
Beschreibungen/Notizen
Bacteria adhere to a surface and, through cell division and coordinated expression of gene products, to develop into a structurally-complex population of adherent cells. This process, known as biofilm formation, requires that intrinsic and extrinsic signals are transduced into appropriate gene expression patterns as biofilms mature. Mutational analysis has begun to reveal the complexity of systems used by
Streptococcus mutans
to ensure proper biofilm formation. These studies have revealed new and unique targets for the design of broadly-effective anti-caries strategies.