Advances in dental research, 2009, Vol.21 (1), p.17-20
2009
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Details
- Autor(en) / Beteiligte
- Titel
- Opportunities for Disrupting Cariogenic Biofilms
- Ist Teil von
- Advances in dental research, 2009, Vol.21 (1), p.17-20
- Ort / Verlag
- United States: SAGE Publications
- Erscheinungsjahr
- 2009
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- Bacteria adhere to a surface and, through cell division and coordinated expression of gene products, to develop into a structurally-complex population of adherent cells. This process, known as biofilm formation, requires that intrinsic and extrinsic signals are transduced into appropriate gene expression patterns as biofilms mature. Mutational analysis has begun to reveal the complexity of systems used by Streptococcus mutans to ensure proper biofilm formation. These studies have revealed new and unique targets for the design of broadly-effective anti-caries strategies.
- Sprache
- Englisch
- Identifikatoren
- ISSN: 0895-9374eISSN: 1544-0737DOI: 10.1177/0895937409335593Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2853230
- Format
- –
- Schlagworte
- Adaptation, Physiological, Biofilms - growth & development, Dental Caries - microbiology, Dentistry, Gene Expression Regulation, Bacterial, Guanosine Tetraphosphate - metabolism, Humans, Hydrogen-Ion Concentration, Oxidation-Reduction, Phosphoenolpyruvate Sugar Phosphotransferase System - metabolism, Reactive Oxygen Species - metabolism, Signal Transduction, Streptococcus mutans - enzymology, Streptococcus mutans - genetics