Small (Weinheim an der Bergstrasse, Germany), 2009-12, Vol.5 (23), p.2673-2677
2009
Details
- Autor(en) / Beteiligte
- Titel
- Co-delivery of Doxorubicin and Bcl-2 siRNA by Mesoporous Silica Nanoparticles Enhances the Efficacy of Chemotherapy in Multidrug-Resistant Cancer Cells
- Ist Teil von
- Small (Weinheim an der Bergstrasse, Germany), 2009-12, Vol.5 (23), p.2673-2677
- Ort / Verlag
- Weinheim: WILEY-VCH Verlag
- Erscheinungsjahr
- 2009
- Link zum Volltext
- Quelle
- Wiley Online Library - AutoHoldings Journals
- Beschreibungen/Notizen
- Co‐delivery of Doxorubicin and siRNAs by mesoporous silica nanoparticles into multidrug‐resistance cancer cells with minimal premature release significantly enhances the efficacy of chemotherapy by conquering the nonpump resistance and possibly bypassing the efflux pump resistance (see image).
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1613-6810eISSN: 1613-6829DOI: 10.1002/smll.200900621Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2833276
- Format
- –
- Schlagworte
- Antineoplastic Agents - administration & dosage, apoptosis, Apoptosis - drug effects, Cell Line, Tumor, Co-delivery, Doxorubicin - administration & dosage, Drug Resistance, Neoplasm, Female, gene expression, Genes, bcl-2, Humans, Microscopy, Electron, Transmission, Microscopy, Fluorescence, Nanoparticles - chemistry, Nanoparticles - ultrastructure, Nanotechnology, Ovarian Neoplasms - drug therapy, Ovarian Neoplasms - genetics, Ovarian Neoplasms - pathology, RNA, Small Interfering - administration & dosage, RNA, Small Interfering - genetics, Silicon Dioxide, simultaneous delivery of drug and siRNA