World journal of gastroenterology : WJG, 2010-01, Vol.16 (1), p.89-97
2010
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- Autor(en) / Beteiligte
- Titel
- On-treatment predictions of success in peg-interferon/ribavirin treatment using a novel formula
- Ist Teil von
- World journal of gastroenterology : WJG, 2010-01, Vol.16 (1), p.89-97
- Ort / Verlag
- United States: Department of Internal Medicine, School of Medicine, Keio University, 35 Shinanomachi, Shinjuku-ku, Tokyo 1608582, Japan
- Erscheinungsjahr
- 2010
- Quelle
- MEDLINE
- Beschreibungen/Notizen
- AIM:To predict treatment success using only simple clinical data from peg-interferon plus ribavirin therapy for chronic hepatitis C. METHODS:We analyzed the clinical data of 176 patients with chronic hepatitis and hepatitis C virus genotype 1 who received 48 wk standard therapy, derived a predictive formula to assess a sustained virological response of the individual patient using a logistic regression model and confirmed the validity of this formula.The formula was constructed using data from the first 100...
- Sprache
- Englisch
- Identifikatoren
- ISSN: 1007-9327eISSN: 2219-2840DOI: 10.3748/wjg.v16.i1.89Titel-ID: cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_2799922
- Format
- –
- Schlagworte
- Adolescent, Adult, Aged, Antiviral Agents - administration & dosage, Brief, Drug Dosage Calculations, Drug Therapy, Combination, Female, Genotype, Hepacivirus - genetics, Hepacivirus - growth & development, Hepatitis C, Chronic - diagnosis, Hepatitis C, Chronic - drug therapy, Humans, Interferon alpha-2, Interferon-alpha - administration & dosage, Kinetics, Logistic Models, Male, Middle Aged, Patient Selection, Polyethylene Glycols - administration & dosage, Predictive Value of Tests, Prospective Studies, Recombinant Proteins, Reproducibility of Results, Ribavirin - administration & dosage, RNA, Viral - blood, ROC Curve, Treatment Outcome, Viral Load, Young Adult